Wyeast 2007 targets German pilsner specifically, and its higher attenuation range — 74-79%, against 2124's 69-73% or 2000's 69-73% — is the clearest marker of that different tradition: German pilsner reads crisper and drier than Czech pilsner's fuller, maltier profile, and 2007's attenuation ceiling reflects that stylistic difference directly rather than being an arbitrary spec.
Like any lager strain, 2007 benefits from true cold fermentation temperatures, a healthy pitch rate, and extended cold conditioning afterward to fully develop clean lager character; the same sulfur-during-fermentation, patience-rewarding profile that applies across this whole family of classic lager strains applies here too. German pilsner and other clean, crisp German lager styles are its clear home — a brewer building a side-by-side comparison of German versus Czech pilsner traditions would reach for 2007 and 2124 respectively as the two strains most directly representing each tradition's real character. Medium-high flocculation gives 2007 somewhat more reliable clearing than the medium-flocculation Bohemian strains, a small but genuine practical convenience worth noting. As with any lager strain, a healthy pitch rate and true cold fermentation temperature matter more to the final result than they would for a comparable-strength ale, since the yeast's own slower reproduction at lager temperatures leaves less room to recover from an underpitched or poorly managed start.